Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc

c-Myc is a transcription factor that is constitutively and aberrantly expressed in over 70% of human cancers. Its direct inhibition has been shown to trigger rapid tumor regression in mice with only mild and fully reversible side effects, suggesting this to be a viable therapeutic strategy. Here we...

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Detalles Bibliográficos
Autores principales: Madden, Sarah K., de Araujo, Aline Dantas, Gerhardt, Mara, Fairlie, David P., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780693/
https://www.ncbi.nlm.nih.gov/pubmed/33397405
http://dx.doi.org/10.1186/s12943-020-01291-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780693/
https://www.ncbi.nlm.nih.gov/pubmed/33397405
http://dx.doi.org/10.1186/s12943-020-01291-6

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