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Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc
c-Myc is a transcription factor that is constitutively and aberrantly expressed in over 70% of human cancers. Its direct inhibition has been shown to trigger rapid tumor regression in mice with only mild and fully reversible side effects, suggesting this to be a viable therapeutic strategy. Here we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780693/ https://www.ncbi.nlm.nih.gov/pubmed/33397405 http://dx.doi.org/10.1186/s12943-020-01291-6 |