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Adaptability of the ubiquitin-proteasome system to proteolytic and folding stressors

Aging, disease, and environmental stressors are associated with failures in the ubiquitin-proteasome system (UPS), yet a quantitative understanding of how stressors affect the proteome and how the UPS responds is lacking. Here we assessed UPS performance and adaptability in yeast under stressors usi...

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Detalles Bibliográficos
Autores principales: Work, Jeremy J., Brandman, Onn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780722/
https://www.ncbi.nlm.nih.gov/pubmed/33382395
http://dx.doi.org/10.1083/jcb.201912041