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Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling

Disulfiram (DSF) is a well-known drug for alcohol abuse. In recent decades, DSF has been demonstrated to exhibit anti-tumor activity; DSF chelated with copper shows enhanced anti-tumor effect. Our goal was to explore the effect of DSF/Cu complex on the growth and metastasis of gastric cancer (GC) in...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Chai, Xiaoke, Wan, Run, Zhang, Hong, Zhou, Cong, Xiang, Lin, Paul, Maswikiti Ewetse, Li, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780754/
https://www.ncbi.nlm.nih.gov/pubmed/33409152
http://dx.doi.org/10.3389/fonc.2020.595718