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Culture substrate‐associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells

Human induced pluripotent stem cells (hiPSCs) are a promising cell source for the creation of cartilage to treat articular cartilage damage. The molecular mechanisms that translate culture conditions to the chondrogenic differentiation of hiPSCs remain to be analyzed. To analyze the effects of cultu...

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Detalles Bibliográficos
Autores principales: Yamashita, Akihiro, Yoshitomi, Hiroyuki, Kihara, Shunsuke, Toguchida, Junya, Tsumaki, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780802/
https://www.ncbi.nlm.nih.gov/pubmed/32822104
http://dx.doi.org/10.1002/sctm.20-0058