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Human induced pluripotent stem cell‐derived lung organoids in an ex vivo model of the congenital diaphragmatic hernia fetal lung

Three‐dimensional lung organoids (LOs) derived from pluripotent stem cells have the potential to enhance our understanding of disease mechanisms and to enable novel therapeutic approaches in neonates with pulmonary disorders. We established a reproducible ex vivo model of lung development using tran...

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Detalles Bibliográficos
Autores principales: Kunisaki, Shaun M., Jiang, Guihua, Biancotti, Juan C., Ho, Kenneth K. Y., Dye, Briana R., Liu, Allen P., Spence, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780804/
https://www.ncbi.nlm.nih.gov/pubmed/32949227
http://dx.doi.org/10.1002/sctm.20-0199