Synaptic Loss in Alzheimer's Disease: Mechanistic Insights Provided by Two-Photon in vivo Imaging of Transgenic Mouse Models

Synapse loss is the strongest correlate for cognitive decline in Alzheimer's disease. The mechanisms underlying synapse loss have been extensively investigated using mouse models expressing genes with human familial Alzheimer's disease mutations. In this review, we summarize how multiphoto...

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Detalles Bibliográficos
Autores principales: Subramanian, Jaichandar, Savage, Julie C., Tremblay, Marie-Ève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780885/
https://www.ncbi.nlm.nih.gov/pubmed/33408613
http://dx.doi.org/10.3389/fncel.2020.592607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780885/
https://www.ncbi.nlm.nih.gov/pubmed/33408613
http://dx.doi.org/10.3389/fncel.2020.592607

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