Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection

Preclinical mouse models that recapitulate some characteristics of coronavirus disease (COVID-19) will facilitate focused study of pathogenesis and virus–host responses. Human agniotensin-converting enzyme 2 (hACE2) serves as an entry receptor for severe acute respiratory syndrome coronavirus 2 (SAR...

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Detalles Bibliográficos
Autores principales: Han, Kun, Blair, Robert V., Iwanaga, Naoki, Liu, Fengming, Russell-Lodrigue, Kasi E., Qin, Zhongnan, Midkiff, Cecily C., Golden, Nadia A., Doyle-Meyers, Lara A., Kabir, Mohammad E., Chandler, Kristin E., Cutrera, Kellie L., Ren, Mi, Monjure, Christopher J., Lehmicke, Gabrielle, Fischer, Tracy, Beddingfield, Brandon, Wanek, Alanna G., Birnbaum, Angela, Maness, Nicholas J., Roy, Chad J., Datta, Prasun K., Rappaport, Jay, Kolls, Jay K., Qin, Xuebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781002/
https://www.ncbi.nlm.nih.gov/pubmed/32991819
http://dx.doi.org/10.1165/rcmb.2020-0354OC

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781002/
https://www.ncbi.nlm.nih.gov/pubmed/32991819
http://dx.doi.org/10.1165/rcmb.2020-0354OC

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