Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases

BACKGROUND: Non-steroidal anti-inflammatory drugs, cyclooxygenase (COX)-2 selective inhibitors, have been explored for prevention and treatment of several inflammatory chronic conditions including arthritis, and cancer. However, the long-term use of these drugs is associated with gastrointestinal, r...

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Detalles Bibliográficos
Autores principales: Yarla, Nagendra Sastri, Pathuri, Gopal, Gali, Hariprasad, Terzyan, Simon, Panneerselvam, Janani, Chandrakesan, Parthasarathy, Scotti, Marcus Tullius, Houchen, Courtney, Madka, Venkateshwar, Rao, Chinthalapally V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781011/
https://www.ncbi.nlm.nih.gov/pubmed/33408499
http://dx.doi.org/10.2147/JIR.S286110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781011/
https://www.ncbi.nlm.nih.gov/pubmed/33408499
http://dx.doi.org/10.2147/JIR.S286110

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