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TRIM47 Promotes the Development of Glioma by Ubiquitination and Degradation of FOXO1

OBJECTIVE: To investigate the effect of TRIM47 on glioma cells and further explore its underlying molecular mechanisms. METHODS: Mouse xenograft model was used in this study. The mRNA expression of TRIM47 was detected by qRT-PCR. The cell viability and proliferation activity was detected by MTT assa...

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Detalles Bibliográficos
Autores principales: Wei, Huaming, Ding, Chonglan, Zhuang, Huanxia, Hu, WeiLi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781021/
https://www.ncbi.nlm.nih.gov/pubmed/33408486
http://dx.doi.org/10.2147/OTT.S264459