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YAP Deficiency Attenuates Pulmonary Injury Following Mechanical Ventilation Through the Regulation of M1/M2 Macrophage Polarization

BACKGROUND: Evidences indicate that the balance between macrophage M1 and M2 polarization is essential for the regulation of pulmonary inflammation during mechanical ventilation (MV). Yes-associated protein (YAP) is a key component of the Hippo pathway and was suggested to regulate macrophage polari...

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Detalles Bibliográficos
Autores principales: Luo, Qiong, Luo, Jing, Wang, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781043/
https://www.ncbi.nlm.nih.gov/pubmed/33408500
http://dx.doi.org/10.2147/JIR.S288244