An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

Mostrar otras versiones (1)

The spike S of SARS-CoV-2 recognizes ACE2 on the host cell membrane to initiate entry. Soluble decoy receptors, in which the ACE2 ectodomain is engineered to block S with high affinity, potently neutralize infection and, due to close similarity with the natural receptor, hold out the promise of bein...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Kui K., Tan, Timothy J.C., Narayanan, Krishna K., Procko, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781310/
https://www.ncbi.nlm.nih.gov/pubmed/33398275
http://dx.doi.org/10.1101/2020.10.18.344622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781310/
https://www.ncbi.nlm.nih.gov/pubmed/33398275
http://dx.doi.org/10.1101/2020.10.18.344622

Ejemplares similares