TCR meta-clonotypes for biomarker discovery with tcrdist3: identification of public, HLA-restricted SARS-CoV-2 associated TCR features

As the mechanistic basis of adaptive cellular antigen recognition, T cell receptors (TCRs) encode clinically valuable information that reflects prior antigen exposure and potential future response. However, despite advances in deep repertoire sequencing, enormous TCR diversity complicates the use of...

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Detalles Bibliográficos
Autores principales: Mayer-Blackwell, Koshlan, Schattgen, Stefan, Cohen-Lavi, Liel, Crawford, Jeremy Chase, Souquette, Aisha, Gaevert, Jessica A., Hertz, Tomer, Thomas, Paul G., Bradley, Philip, Fiore-Gartland, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781332/
https://www.ncbi.nlm.nih.gov/pubmed/33398288
http://dx.doi.org/10.1101/2020.12.24.424260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781332/
https://www.ncbi.nlm.nih.gov/pubmed/33398288
http://dx.doi.org/10.1101/2020.12.24.424260

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