miRNA expression and interaction with the 3′UTR of FMR1 in FRAXopathy pathogenesis

FRAXopathies are caused by the expansion of the CGG repeat in the 5′UTR of the FMR1 gene, which encodes the protein responsible for the synthesis of FMRP. This mutation leads to dramatic changes in FMRP expression at both the mRNA and protein levels. Evidence is emerging that changes in FMR1 mRNA ex...

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Detalles Bibliográficos
Autores principales: Dolskiy, Alexander A., Yarushkin, Andrey A., Grishchenko, Irina V., Lemskaya, Natalya A., Pindyurin, Alexey V., Boldyreva, Lidiya V., Pustylnyak, Vladimir O., Yudkin, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781359/
https://www.ncbi.nlm.nih.gov/pubmed/33426406
http://dx.doi.org/10.1016/j.ncrna.2020.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781359/
https://www.ncbi.nlm.nih.gov/pubmed/33426406
http://dx.doi.org/10.1016/j.ncrna.2020.11.006

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