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Tanshinone IIA Promotes M2 Microglia by ERβ/IL-10 Pathway and Attenuates Neuronal Loss in Mouse TBI Model

PURPOSE: Traumatic brain injury (TBI) is a major cause of morbidity and mortality worldwide. Increasing evidence indicates that activated microglia play an important role in the inflammatory response in TBI. Inhibiting M1 and stimulating M2 activated microglia have protective effects in several anim...

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Detalles Bibliográficos
Autores principales: Chen, Mingrui, Chen, Qiulin, Tao, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781361/
https://www.ncbi.nlm.nih.gov/pubmed/33408474
http://dx.doi.org/10.2147/NDT.S265478