Risk Characterization and Probabilistic Concentration–Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic in Vitro Human Stem Cell Assays

BACKGROUND: Risk assessment of chemical mixtures or complex substances remains a major methodological challenge due to lack of available hazard or exposure data. Therefore, risk assessors usually infer hazard or risk from data on the subset of constituents with available toxicity values. OBJECTIVES:...

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Detalles Bibliográficos
Autores principales: Hsieh, Nan-Hung, Chen, Zunwei, Rusyn, Ivan, Chiu, Weihsueh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781439/
https://www.ncbi.nlm.nih.gov/pubmed/33395322
http://dx.doi.org/10.1289/EHP7600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781439/
https://www.ncbi.nlm.nih.gov/pubmed/33395322
http://dx.doi.org/10.1289/EHP7600

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