Cargando…
Risk Characterization and Probabilistic Concentration–Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic in Vitro Human Stem Cell Assays
BACKGROUND: Risk assessment of chemical mixtures or complex substances remains a major methodological challenge due to lack of available hazard or exposure data. Therefore, risk assessors usually infer hazard or risk from data on the subset of constituents with available toxicity values. OBJECTIVES:...
Autores principales: | Hsieh, Nan-Hung, Chen, Zunwei, Rusyn, Ivan, Chiu, Weihsueh A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781439/ https://www.ncbi.nlm.nih.gov/pubmed/33395322 http://dx.doi.org/10.1289/EHP7600 |
Ejemplares similares
-
Cumulative Risk Meets Inter-Individual Variability: Probabilistic Concentration Addition of Complex Mixture Exposures in a Population-Based Human In Vitro Model
por: Jang, Suji, et al.
Publicado: (2022) -
Rapid Hazard Characterization of Environmental Chemicals Using a Compendium of Human Cell Lines from Different Organs
por: Chen, Zunwei, et al.
Publicado: (2020) -
A human population-based organotypic in vitro model for cardiotoxicity screening
por: Grimm, Fabian A., et al.
Publicado: (2018) -
A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures
por: Ford, Lucie C., et al.
Publicado: (2022) -
Evaluation of Metabolism of a Defined Pesticide Mixture through Multiple In Vitro Liver Models
por: Valdiviezo, Alan, et al.
Publicado: (2022)