A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR

Cells use a variety of mechanisms to maintain optimal mitochondrial function including the mitochondrial unfolded protein response (UPR(mt)). The UPR(mt) mitigates mitochondrial dysfunction by differentially regulating mitoprotective gene expression through the transcription factor ATFS-1. Since UPR...

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Detalles Bibliográficos
Autores principales: Amin, Mustafi Raisa, Mahmud, Siraje Arif, Dowgielewicz, Jonathan L., Sapkota, Madhab, Pellegrino, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781476/
https://www.ncbi.nlm.nih.gov/pubmed/33338044
http://dx.doi.org/10.1371/journal.pgen.1009234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781476/
https://www.ncbi.nlm.nih.gov/pubmed/33338044
http://dx.doi.org/10.1371/journal.pgen.1009234

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