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Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales

BACKGROUND & AIM: Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD) that is responsible for a growing fraction of cirrhosis and liver cancer cases worldwide. Changes in the gut microbiome have been implicated in NASH pathogenesis, but the lack of...

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Detalles Bibliográficos
Autores principales: Carter, James K., Bhattacharya, Dipankar, Borgerding, Joshua N., Fiel, M. Isabel, Faith, Jeremiah J., Friedman, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781477/
https://www.ncbi.nlm.nih.gov/pubmed/33395434
http://dx.doi.org/10.1371/journal.pone.0244763