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Dysregulated PJA1-TGF-β signaling in cancer stem cell–associated liver cancers
The transforming growth factor beta (TGF-β) signaling pathway plays important roles in cell differentiation, stem cell modulation, organ lineage, and immune suppression. TGF-β signaling is negatively regulated by the ubiquitin–proteasome pathway. Although mouse models of cancer arising from a defect...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781490/ https://www.ncbi.nlm.nih.gov/pubmed/33457451 http://dx.doi.org/10.18632/oncoscience.522 |