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Dysregulated PJA1-TGF-β signaling in cancer stem cell–associated liver cancers

The transforming growth factor beta (TGF-β) signaling pathway plays important roles in cell differentiation, stem cell modulation, organ lineage, and immune suppression. TGF-β signaling is negatively regulated by the ubiquitin–proteasome pathway. Although mouse models of cancer arising from a defect...

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Detalles Bibliográficos
Autores principales: Chen, Jian, A. Gingold, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781490/
https://www.ncbi.nlm.nih.gov/pubmed/33457451
http://dx.doi.org/10.18632/oncoscience.522