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Dysregulated PJA1-TGF-β signaling in cancer stem cell–associated liver cancers

The transforming growth factor beta (TGF-β) signaling pathway plays important roles in cell differentiation, stem cell modulation, organ lineage, and immune suppression. TGF-β signaling is negatively regulated by the ubiquitin–proteasome pathway. Although mouse models of cancer arising from a defect...

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Detalles Bibliográficos
Autores principales:	Chen, Jian, A. Gingold, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781490/ https://www.ncbi.nlm.nih.gov/pubmed/33457451 http://dx.doi.org/10.18632/oncoscience.522

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