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Kv1.3 inhibition attenuates neuroinflammation through disruption of microglial calcium signaling

In the last 5 years inhibitors of the potassium channel K(V)1.3 have been shown to reduce neuroinflammation in rodent models of ischemic stroke, Alzheimer’s disease, Parkinson’s disease and traumatic brain injury. At the systemic level these beneficial actions are mediated by a reduction in microgli...

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Detalles Bibliográficos
Autores principales: Fomina, Alla F., Nguyen, Hai M., Wulff, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781540/
https://www.ncbi.nlm.nih.gov/pubmed/33356832
http://dx.doi.org/10.1080/19336950.2020.1853943