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The vascular niche controls Drosophila hematopoiesis via fibroblast growth factor signaling

In adult mammals, hematopoiesis, the production of blood cells from hematopoietic stem and progenitor cells (HSPCs), is tightly regulated by extrinsic signals from the microenvironment called ‘niche’. Bone marrow HSPCs are heterogeneous and controlled by both endosteal and vascular niches. The Droso...

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Detalles Bibliográficos
Autores principales: Destalminil-Letourneau, Manon, Morin-Poulard, Ismaël, Tian, Yushun, Vanzo, Nathalie, Crozatier, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781598/
https://www.ncbi.nlm.nih.gov/pubmed/33395389
http://dx.doi.org/10.7554/eLife.64672