Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest

Different subsets of the tRNA pool in human cells are expressed in different cellular conditions. The ‘proliferation-tRNAs’ are induced upon normal and cancerous cell division, while the ‘differentiation-tRNAs’ are active in non-dividing, differentiated cells. Here we examine the essentiality of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Aharon-Hefetz, Noa, Frumkin, Idan, Mayshar, Yoav, Dahan, Orna, Pilpel, Yitzhak, Rak, Roni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781600/
https://www.ncbi.nlm.nih.gov/pubmed/33357381
http://dx.doi.org/10.7554/eLife.58461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781600/
https://www.ncbi.nlm.nih.gov/pubmed/33357381
http://dx.doi.org/10.7554/eLife.58461

Ejemplares similares