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Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest
Different subsets of the tRNA pool in human cells are expressed in different cellular conditions. The ‘proliferation-tRNAs’ are induced upon normal and cancerous cell division, while the ‘differentiation-tRNAs’ are active in non-dividing, differentiated cells. Here we examine the essentiality of the...
Autores principales: | Aharon-Hefetz, Noa, Frumkin, Idan, Mayshar, Yoav, Dahan, Orna, Pilpel, Yitzhak, Rak, Roni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781600/ https://www.ncbi.nlm.nih.gov/pubmed/33357381 http://dx.doi.org/10.7554/eLife.58461 |
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