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Characterization of the adiponectin promoter + Cre recombinase insertion in the Tg(Adipoq-cre)1Evdr mouse by targeted locus amplification and droplet digital PCR
The Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. Using Targeted Locus Amplification (TLA) we found the transgene had integrated on mouse chromosome 9 between exons 6 and 7 of Tbx18. W...
Autores principales: | Wong, Adrian M., Patel, Tushar P., Altman, Elizabeth K., Tugarinov, Nicol, Trivellin, Giampaolo, Yanovski, Jack A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781622/ https://www.ncbi.nlm.nih.gov/pubmed/33371773 http://dx.doi.org/10.1080/21623945.2020.1861728 |
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