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The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice

Extibacter muris is a newly described mouse gut bacterium which metabolizes cholic acid (CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence metabolic and inflammatory responses, few in vivo models exist for studying their metabolism and impact on the host. Mice were...

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Detalles Bibliográficos
Autores principales: Streidl, Theresa, Karkossa, Isabel, Segura Muñoz, Rafael R., Eberl, Claudia, Zaufel, Alex, Plagge, Johannes, Schmaltz, Robert, Schubert, Kristin, Basic, Marijana, Schneider, Kai Markus, Afify, Mamdouh, Trautwein, Christian, Tolba, René, Stecher, Bärbel, Doden, Heidi L., Ridlon, Jason M., Ecker, Josef, Moustafa, Tarek, von Bergen, Martin, Ramer-Tait, Amanda E., Clavel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781625/
https://www.ncbi.nlm.nih.gov/pubmed/33382950
http://dx.doi.org/10.1080/19490976.2020.1854008