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Adhesion stimulates Scar/WAVE phosphorylation in mammalian cells

The Scar/WAVE complex catalyzes the protrusion of pseudopods and lamellipods, and is therefore a principal regulator of cell migration. However, it is unclear how its activity is regulated, beyond a dependence on Rac. Phosphorylation of the proline-rich region, by kinases such as Erk2, has been sugg...

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Detalles Bibliográficos
Autores principales: Singh, Shashi Prakash, Insall, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781634/
https://www.ncbi.nlm.nih.gov/pubmed/33447346
http://dx.doi.org/10.1080/19420889.2020.1855854