Cargando…

Trigeminal neuropathic pain is alleviated by inhibition of Ca(v)3.3 T-type calcium channels in mice

In this brief report, we demonstrate that the Ca(v)3.3 T-type voltage-gated calcium channel subtype is involved in our FRICT-ION model of chronic trigeminal neuropathic pain. We first showed that the Cacna1i gene encoding Ca(v)3.3 is significantly upregulated in whole trigeminal ganglia of FRICT-ION...

Descripción completa

Detalles Bibliográficos
Autores principales: Montera, Marena, Goins, Aleyah, Cmarko, Leos, Weiss, Norbert, Westlund, Karin N., Alles, Sascha R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781641/
https://www.ncbi.nlm.nih.gov/pubmed/33283622
http://dx.doi.org/10.1080/19336950.2020.1859248