Cargando…
Trigeminal neuropathic pain is alleviated by inhibition of Ca(v)3.3 T-type calcium channels in mice
In this brief report, we demonstrate that the Ca(v)3.3 T-type voltage-gated calcium channel subtype is involved in our FRICT-ION model of chronic trigeminal neuropathic pain. We first showed that the Cacna1i gene encoding Ca(v)3.3 is significantly upregulated in whole trigeminal ganglia of FRICT-ION...
Autores principales: | Montera, Marena, Goins, Aleyah, Cmarko, Leos, Weiss, Norbert, Westlund, Karin N., Alles, Sascha R. A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781641/ https://www.ncbi.nlm.nih.gov/pubmed/33283622 http://dx.doi.org/10.1080/19336950.2020.1859248 |
Ejemplares similares
-
Selective inhibition of neuronal Ca(v)3.3 T-type calcium channels by TAT-based channel peptide
por: Cmarko, Leos, et al.
Publicado: (2020) -
Pre- and Post-Interventional Changes in Physiological Profiles in a Patient Presenting With Opioid Withdrawal After Intrathecal Drug Delivery System Failure Related to Assumed Catheter Microfracture
por: Ehsanian, Reza, et al.
Publicado: (2021) -
Sustained relief of trigeminal neuropathic pain by a blood–brain barrier penetrable PPAR gamma agonist
por: Zhang, Morgan, et al.
Publicado: (2019) -
Single-Dose P2 X4R Single-Chain Fragment Variable Antibody Permanently Reverses Chronic Pain in Male Mice
por: Westlund, Karin N., et al.
Publicado: (2021) -
Identification of a molecular gating determinant within the carboxy terminal region of Ca(v)3.3 T-type channels
por: Jurkovicova-Tarabova, Bohumila, et al.
Publicado: (2019)