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Functional modulation of the human voltage-gated sodium channel Na(V)1.8 by auxiliary β subunits

The voltage-gated sodium channel Na(v)1.8 mediates the tetrodotoxin-resistant (TTX-R) Na(+) current in nociceptive primary sensory neurons, which has an important role in the transmission of painful stimuli. Here, we describe the functional modulation of the human Na(v)1.8 α-subunit in Xenopus oocyt...

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Detalles Bibliográficos
Autores principales: Nevin, S. T., Lawrence, N., Nicke, A., Lewis, R. J., Adams, D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781643/
https://www.ncbi.nlm.nih.gov/pubmed/33315536
http://dx.doi.org/10.1080/19336950.2020.1860399