Synthesis of some quinazolinones inspired from the natural alkaloid L-norephedrine as EGFR inhibitors and radiosensitizers

A set of quinazolinones synthesized by the aid of L-norephedrine was assembled to generate novel analogues as potential anticancer and radiosensitizing agents. The new compounds were evaluated for their cytotoxic activity against MDA-MB-231, MCF-7, HepG-2, HCT-116 cancer cell lines and EGFR inhibito...

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Detalles Bibliográficos
Autores principales: Ghorab, Mostafa M., Abdel-Kader, Maged S., Alqahtani, Ali S., Soliman, Aiten M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781899/
https://www.ncbi.nlm.nih.gov/pubmed/33357002
http://dx.doi.org/10.1080/14756366.2020.1854243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781899/
https://www.ncbi.nlm.nih.gov/pubmed/33357002
http://dx.doi.org/10.1080/14756366.2020.1854243

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