Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression

BACKGROUND: Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. METHODS: Wild-type and Sesn2 knockout (KO) mice of the 129/SvJ background were maintained in a...

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Detalles Bibliográficos
Autores principales: Hwang, Chae Young, Han, Ying-Hao, Lee, Seung-Min, Cho, Sang-Mi, Yu, Dae-Yeul, Kwon, Ki-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Geriatrics Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781962/
https://www.ncbi.nlm.nih.gov/pubmed/33227845
http://dx.doi.org/10.4235/agmr.20.0051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781962/
https://www.ncbi.nlm.nih.gov/pubmed/33227845
http://dx.doi.org/10.4235/agmr.20.0051

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