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Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression
BACKGROUND: Sestrin2 (Sesn2) is involved in the maintenance of metabolic homeostasis and aging via modulation of the 5' AMP-activated protein kinase-mammalian target of rapamycin (AMPK-mTOR) pathway. METHODS: Wild-type and Sesn2 knockout (KO) mice of the 129/SvJ background were maintained in a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Geriatrics Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781962/ https://www.ncbi.nlm.nih.gov/pubmed/33227845 http://dx.doi.org/10.4235/agmr.20.0051 |