First structure–activity relationship analysis of SARS-CoV-2 virus main protease (Mpro) inhibitors: an endeavor on COVID-19 drug discovery

ABSTRACT: Main protease (Mpro) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) intervenes in the replication and transcription processes of the virus. Hence, it is a lucrative target for anti-viral drug development. In this study, molecular modeling analyses were performed on the str...

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Detalles Bibliográficos
Autores principales: Amin, Sk. Abdul, Banerjee, Suvankar, Singh, Samayaditya, Qureshi, Insaf Ahmed, Gayen, Shovanlal, Jha, Tarun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782049/
https://www.ncbi.nlm.nih.gov/pubmed/33400085
http://dx.doi.org/10.1007/s11030-020-10166-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782049/
https://www.ncbi.nlm.nih.gov/pubmed/33400085
http://dx.doi.org/10.1007/s11030-020-10166-3

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