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SIK2 represses AKT/GSK3β/β‐catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases

Salt‐inducible kinase 2 (SIK2) is an important regulator in various intracellular signaling pathways related to apoptosis, tumorigenesis and metastasis. However, the involvement of SIK2 in gastric tumorigenesis and the functional linkage with gastric cancer (GC) progression remain to be defined. Her...

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Detalles Bibliográficos
Autores principales: Dai, Xiao‐man, Zhang, Yan‐hui, Lin, Xiao‐han, Huang, Xiao‐xing, Zhang, Yi, Xue, Chao‐rong, Chen, Wan‐nan, Ye, Jian‐xin, Lin, Xin‐jian, Lin, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782074/
https://www.ncbi.nlm.nih.gov/pubmed/33128264
http://dx.doi.org/10.1002/1878-0261.12838