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EBP2, a novel NPM‐ALK‐interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53

The oncogenic fusion protein nucleophosmin‐anaplastic lymphoma kinase (NPM‐ALK), found in anaplastic large‐cell lymphoma (ALCL), localizes to the cytosol, nucleoplasm, and nucleolus. However, the relationship between its localization and transforming activity remains unclear. We herein demonstrated...

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Detalles Bibliográficos
Autores principales: Uchihara, Yuki, Tago, Kenji, Tamura, Hiroomi, Funakoshi‐Tago, Megumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782078/
https://www.ncbi.nlm.nih.gov/pubmed/33040459
http://dx.doi.org/10.1002/1878-0261.12822