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The KRAS/Lin28B axis maintains stemness of pancreatic cancer cells via the let‐7i/TET3 pathway

Increasing evidence demonstrates that Lin28B plays critical roles in numerous biological processes including cell proliferation and stemness maintenance. However, the molecular mechanisms underlying Lin28B nuclear translocation remain poorly understood. Here, we found for the first time that KRAS pr...

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Detalles Bibliográficos
Autores principales: Liu, Yawen, Wang, Dawei, Zhou, Meng, Chen, Hui, Wang, Huizhi, Min, Jingyu, Chen, Jiaxi, Wu, Shuhui, Ni, Xiufan, Zhang, Youli, Gong, Aihua, Xu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782082/
https://www.ncbi.nlm.nih.gov/pubmed/33107691
http://dx.doi.org/10.1002/1878-0261.12836