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5‐Hydroxymethylcytosine signature in circulating cell‐free DNA as a potential diagnostic factor for early‐stage colorectal cancer and precancerous adenoma

Approximately 85% colorectal cancers (CRCs) are thought to evolve through the adenoma‐to‐carcinoma sequence associated with specific molecular alterations, including the 5‐hydroxymethylcytosine (5hmC) signature in circulating cell‐free DNA (cfDNA). To explore colorectal disease progression and evalu...

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Detalles Bibliográficos
Autores principales: Xiao, ZeWen, Wu, Wendy, Wu, Chunlong, Li, Man, Sun, Fuming, Zheng, Lu, Liu, Gaojing, Li, Xiaoling, Yun, Zhiyuan, Tang, Jiebing, Yu, Yang, Luo, Shengnan, Sun, Wenji, Feng, Xiaohong, Cheng, Qian, Tao, Xue, Wu, Shuangxiu, Tao, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782095/
https://www.ncbi.nlm.nih.gov/pubmed/33107199
http://dx.doi.org/10.1002/1878-0261.12833