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α-Hederin inhibits the growth of lung cancer A549 cells in vitro and in vivo by decreasing SIRT6 dependent glycolysis

CONTEXT: α-Hederin, a potent bioactive compound of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae), has many pharmacological uses, but its effect on cancer cell metabolism is still unclear. OBJECTIVE: To elucidate the role of α-hederin in the glucose metabolism of lung cancer cells. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Fang, Cong, Liu, Yahui, Chen, Lanying, Luo, Yingying, Cui, Yaru, Zhang, Ni, Liu, Peng, Zhou, Mengjing, Xie, Yongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782159/
https://www.ncbi.nlm.nih.gov/pubmed/33356727
http://dx.doi.org/10.1080/13880209.2020.1862250