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Anticancer active trifluoromethylated fused triazinones are safe for early-life stages of zebrafish (Danio rerio) and reveal a proapoptotic action

The main purpose of this investigation was to evaluate the effect of anticancer active compounds (I–VIII) on zebrafish development in order to select the safest molecules. Larval mortality, embryo hatchability and malformations were end-points used to assess the acute toxicity among embryos and larv...

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Detalles Bibliográficos
Autores principales: Sztanke, Małgorzata, Rzymowska, Jolanta, Sztanke, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782186/
https://www.ncbi.nlm.nih.gov/pubmed/33390035
http://dx.doi.org/10.1080/14756366.2020.1865944