Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria

We developed an orally administered, engineered, bacterium-based, RNA interference-mediated therapeutic method to significantly reduce the symptoms in the most frequently used animal model of inflammatory bowel disease. This bacterium-mediated RNA interference strategy was based on the genomically s...

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Detalles Bibliográficos
Autores principales: Ferenczi, Szilamer, Solymosi, Norbert, Horváth, István, Szeőcs, Natália, Grózer, Zsuzsanna, Kuti, Dániel, Juhász, Balázs, Winkler, Zsuzsanna, Pankotai, Tibor, Sükösd, Farkas, Stágel, Anikó, Paholcsek, Melinda, Dóra, Dávid, Nagy, Nándor, Kovács, Krisztina J., Zanoni, Ivan, Szallasi, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782194/
https://www.ncbi.nlm.nih.gov/pubmed/33426148
http://dx.doi.org/10.1016/j.omtm.2020.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782194/
https://www.ncbi.nlm.nih.gov/pubmed/33426148
http://dx.doi.org/10.1016/j.omtm.2020.11.010

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