Cargando…

A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications

Surfactant protein B (SPB) deficiency is a severe monogenic interstitial lung disorder that leads to loss of life in infants as a result of alveolar collapse and respiratory distress syndrome. The development and assessment of curative therapies for the deficiency are limited by the general lack of...

Descripción completa

Detalles Bibliográficos
Autores principales: Munis, Altar M., Hyde, Stephen C., Gill, Deborah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782204/
https://www.ncbi.nlm.nih.gov/pubmed/33426150
http://dx.doi.org/10.1016/j.omtm.2020.11.013