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A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications
Surfactant protein B (SPB) deficiency is a severe monogenic interstitial lung disorder that leads to loss of life in infants as a result of alveolar collapse and respiratory distress syndrome. The development and assessment of curative therapies for the deficiency are limited by the general lack of...
Autores principales: | Munis, Altar M., Hyde, Stephen C., Gill, Deborah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782204/ https://www.ncbi.nlm.nih.gov/pubmed/33426150 http://dx.doi.org/10.1016/j.omtm.2020.11.013 |
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