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Chemotherapy induced damage to spermatogonial stem cells in prepubertal mouse in vitro impairs long-term spermatogenesis

Chemotherapy can affect testis development of young boys with cancer, reducing the chances of fatherhood in adulthood. Studies using experimental models are needed to determine the damage caused by individual chemotherapy drugs in order to predict the risk of infertility and direct patients towards...

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Detalles Bibliográficos
Autores principales: Lopes, Federica, Tholeti, Prathima, Adiga, Satish K., Anderson, Richard A., Mitchell, Rod T., Spears, Norah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782321/
https://www.ncbi.nlm.nih.gov/pubmed/33425685
http://dx.doi.org/10.1016/j.toxrep.2020.12.023