Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC

The renal distal convoluted tubule (DCT) is critical for the fine-tuning of urinary ion excretion and the control of blood pressure. Ion transport along the DCT is tightly controlled by posttranscriptional mechanisms including a complex interplay of kinases, phosphatases, and ubiquitin ligases. Prev...

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Detalles Bibliográficos
Autores principales: Schnoz, Christina, Moser, Sandra, Kratschmar, Denise V., Odermatt, Alex, Loffing-Cueni, Dominique, Loffing, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782375/
https://www.ncbi.nlm.nih.gov/pubmed/33200256
http://dx.doi.org/10.1007/s00424-020-02491-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782375/
https://www.ncbi.nlm.nih.gov/pubmed/33200256
http://dx.doi.org/10.1007/s00424-020-02491-1

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