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β-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia

Carotid body (CB) hyperactivity promotes hypertension in response to chronic intermittent hypoxia (CIH). The plasma concentration of adrenaline is reported to be elevated in CIH and our previous work suggests that adrenaline directly activates the CB. However, a role for chronic adrenergic stimulati...

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Detalles Bibliográficos
Autores principales: Alzahrani, Abdulaziz A., Cao, Lily L., Aldossary, Hayyaf S., Nathanael, Demitris, Fu, Jiarong, Ray, Clare J., Brain, Keith L., Kumar, Prem, Coney, Andrew M., Holmes, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782391/
https://www.ncbi.nlm.nih.gov/pubmed/33210151
http://dx.doi.org/10.1007/s00424-020-02492-0