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Proof-of-Concept Study of the NOTI Chelating Platform: Preclinical Evaluation of (64)Cu-Labeled Mono- and Trimeric c(RGDfK) Conjugates

PURPOSE: We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three five-membered azaheterocyclic arms for the preparation of (68)Ga- and (64)Cu-based radiopharmaceuticals. Based on this platform, the chelator scaffold NOTI-TVA with three additional c...

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Detalles Bibliográficos
Autores principales: Martin, Sebastian, Maus, Stephan, Stemler, Tobias, Rosar, Florian, Khreish, Fadi, Holland, Jason P., Ezziddin, Samer, Bartholomä, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782405/
https://www.ncbi.nlm.nih.gov/pubmed/32856224
http://dx.doi.org/10.1007/s11307-020-01530-8