Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes

In the male germ cells of placental mammals, 26–30-nt-long PIWI-interacting RNAs (piRNAs) emerge when spermatocytes enter the pachytene phase of meiosis. In mice, pachytene piRNAs derive from ~100 discrete autosomal loci that produce canonical RNA polymerase II transcripts. These piRNA clusters bear...

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Detalles Bibliográficos
Autores principales: Yu, Tianxiong, Fan, Kaili, Özata, Deniz M., Zhang, Gen, Fu, Yu, Theurkauf, William E., Zamore, Phillip D., Weng, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782496/
https://www.ncbi.nlm.nih.gov/pubmed/33397987
http://dx.doi.org/10.1038/s41467-020-20345-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782496/
https://www.ncbi.nlm.nih.gov/pubmed/33397987
http://dx.doi.org/10.1038/s41467-020-20345-3

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