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Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes
In the male germ cells of placental mammals, 26–30-nt-long PIWI-interacting RNAs (piRNAs) emerge when spermatocytes enter the pachytene phase of meiosis. In mice, pachytene piRNAs derive from ~100 discrete autosomal loci that produce canonical RNA polymerase II transcripts. These piRNA clusters bear...
Autores principales: | Yu, Tianxiong, Fan, Kaili, Özata, Deniz M., Zhang, Gen, Fu, Yu, Theurkauf, William E., Zamore, Phillip D., Weng, Zhiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782496/ https://www.ncbi.nlm.nih.gov/pubmed/33397987 http://dx.doi.org/10.1038/s41467-020-20345-3 |
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